Article
Seeking completeness in bacterial mutant hunts.
Current opinion in microbiology - 1 Jun 2006
Salama Nina R, Manoil Colin
Abstract excerpt
The identification of most or all of the genetic functions that are required for a particular biological process could be achieved through phenotypic studies of high genome-coverage mutant collections. Technologies for creating such collections, in the form of mixed populations or individually arrayed sequence-defined mutants, are now available for numerous bacterial species. The analysis of mixed mutant...
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