Article
Competitive genomic screens of barcoded yeast libraries.
Journal of visualized experiments : JoVE - 11 Aug 2011
Smith Andrew M, Durbic Tanja, Oh Julia, Urbanus Malene, Proctor Michael, Heisler Lawrence E, Giaever Guri, Nislow Corey
Abstract excerpt
By virtue of advances in next generation sequencing technologies, we have access to new genome sequences almost daily. The tempo of these advances is accelerating, promising greater depth and breadth. In light of these extraordinary advances, the need for fast, parallel methods to define gene function becomes ever more important. Collections of genome-wide deletion mutants in yeasts and E. coli have served as...
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