Article
Association analysis of chromosome 5 GABAA receptor cluster in Japanese schizophrenia patients.
Biological psychiatry - 15 Sept 2005
Ikeda Masashi, Iwata Nakao, Suzuki Tatsuyo, Kitajima Tsuyoshi, Yamanouchi Yoshio, Kinoshita Yoko, Inada Toshiya, Ujike Hiroshi, Ozaki Norio
Abstract excerpt
BACKGROUND: Several investigations suggest that abnormalities in gamma-amino butyric acid (GABA) neurotransmission systems may be related to the pathophysiology of schizophrenia. A GABA(A) receptor gene cluster on 5q31-35 (beta2 [GABRB2], alpha6 [GABRA6], alpha1 [GABRA1], and gamma2 [GABRG2] subunit genes) is one of the most attractive candidate regions for schizophrenia susceptibility. METHODS: We performed 1)...
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