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Article

Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism.

American journal of human genetics - 1 Sept 2005

Ma D Q, Whitehead P L, Menold M M, Martin E R, Ashley-Koch A E, Mei H, Ritchie M D, Delong G R, Abramson R K, Wright H H, Cuccaro M L, Hussman J P, Gilbert J R, Pericak-Vance M A

Abstract excerpt

Autism is a common neurodevelopmental disorder with a significant genetic component. Existing research suggests that multiple genes contribute to autism and that epigenetic effects or gene-gene interactions are likely contributors to autism risk. However, these effects have not yet been identified. Gamma-aminobutyric acid (GABA), the primary inhibitory neurotransmitter in the adult brain, has been implicated in...

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Source

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Identifiers

PMID: 16080114
DOI: 10.1086/433195
PMCID: PMC1226204

Genes

GABRA4
GABRB1
GABRA2
GABRB2
GABRR2
GABRA1
GABRA5
GABRA6
GABRB3
GABRG1
GABRG2
GABRG3
GABRP
GABRR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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