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Article

The impact of telomere erosion on memory CD8+ T cells in patients with X-linked lymphoproliferative syndrome.

Mechanisms of ageing and development - 1 Aug 2005

Plunkett Fiona J, Franzese Ornella, Belaramani Lavina L, Fletcher Jean M, Gilmour Kimberly C, Sharifi Reza, Khan Naeem, Hislop Andrew D, Cara Andrea, Salmon Mike, Gaspar H Bobby, Rustin Malcom H A, Webster David, Akbar Arne N

Abstract excerpt

Patients with X-linked lymphoproliferative syndrome (XLP) experience excessive T cell proliferation after primary Epstein-Barr virus (EBV) infection, due to mutations in the signalling lymphocyte activation molecule (SLAM) associated protein (SAP) molecule. We examined the impact of dysfunctional proliferative control on the extent of CD8+ T cell differentiation in XLP patients who recovered from primary EBV...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15992610
DOI: 10.1016/j.mad.2005.03.006

Genes

CCR7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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The impact of telomere erosion on memory CD8+ T cells in patients with X-linked lymphoproliferative syndrome.PMID 15992610Read ↗

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