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Article

Defective NK cell activation in X-linked lymphoproliferative disease.

Journal of immunology (Baltimore, Md. : 1950) - 1 Oct 2000

Benoit L, Wang X, Pabst H F, Dutz J, Tan R

Abstract excerpt

X-linked lymphoproliferative disease (XLP) is characterized by a selective immune deficiency to EBV. The molecular basis of XLP has been attributed to mutations of signaling lymphocytic activation molecule-associated protein, an intracellular molecule known to associate with the lymphocyte-activating surface receptors SLAM and 2B4. We have identified a single nucleotide mutation in SLAM-associated protein that...

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Source

Identifiers

PMID: 11034354
DOI: 10.4049/jimmunol.165.7.3549

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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