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Article

Kinetics and thermodynamics make different contributions to RNA folding in vitro and in yeast.

Molecular cell - 1 Jul 2005

Mahen Elisabeth M, Harger Jason W, Calderon Elise M, Fedor Martha J

Abstract excerpt

RNAs somehow adopt specific functional structures despite the capacity to form alternative nonfunctional structures with similar stabilities. We analyzed RNA assembly during transcription in vitro and in yeast using hairpin ribozyme self-cleavage to assess partitioning between functional ribozyme structures and nonfunctional stem loops. Complementary insertions located upstream of the ribozyme inhibited ribozyme...

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Source

Identifiers

PMID: 15989962
DOI: 10.1016/j.molcel.2005.05.025

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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