Article
Hierarchy and dynamics of RNA folding.
Annual review of biophysics and biomolecular structure - 1 Jan 1997
Brion P, Westhof E
Abstract excerpt
The evidence showing that the self-assembly of complex RNAs occurs in discrete transitions, each relating to the folding of sub-systems of increasing size and complexity starting from a state with most of the secondary structure, is reviewed. The reciprocal influence of the concentration of magnesium ions and nucleotide mutations on tertiary structure is analyzed. Several observations demonstrate that detrimental...
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