Article
A pause for thought along the co-translational folding pathway.
Trends in biochemical sciences - 1 Jan 2009
Komar Anton A
Abstract excerpt
A unifying concept that combines the basic features governing self-organization of proteins into complex three-dimensional structures in vitro and in vivo is still lacking. Recent experimental results and theoretical in silico modeling studies provide evidence showing that mRNA might contain an additional layer of information, beyond the amino acid sequence, that fine-tunes in vivo protein folding, which is...
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