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Article

Dendritic cells are defective in breast cancer patients: a potential role for polyamine in this immunodeficiency.

Breast cancer research : BCR - 1 Jan 2005

Gervais Alban, Levêque Jean, Bouet-Toussaint Françoise, Burtin Florence, Lesimple Thierry, Sulpice Laurent, Patard Jean-Jacques, Genetet Noelle, Catros-Quemener Véronique

Abstract excerpt

INTRODUCTION: Dendritic cells (DCs) are antigen-presenting cells that are currently employed in cancer clinical trials. However, it is not clear whether their ability to induce tumour-specific immune responses when they are isolated from cancer patients is reduced relative to their ability in vivo. We determined the phenotype and functional activity of DCs from cancer patients and investigated the effect of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15987427
DOI: 10.1186/bcr1001
PMCID: PMC1143555

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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