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Cellular Immunotherapy with Dendritic Cells in Cancer: Current Status

1 Jul 2004

Abstract excerpt

Dendritic cells (DCs) are specialized antigen-presenting cells whose immunogenicity leads to the induction of antigen-specific immune responses. DCs can easily be generated ex vivo from peripheral blood monocytes or bone marrow/circulating hematopoietic stem cells cultured in the presence of cytokine cocktails. DCs have been used in numerous clinical trials to induce antitumor immune responses in cancer patients....

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PMID: 15277696
DOI: 10.1634/stemcells.22-4-501

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