Article
Presentation of renal tumor antigens by human dendritic cells activates tumor-infiltrating lymphocytes against autologous tumor: implications for live kidney cancer vaccines.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Feb 1999
Mulders P, Tso C L, Gitlitz B, Kaboo R, Hinkel A, Frand S, Kiertscher S, Roth M D, deKernion J, Figlin R, Belldegrun A
Abstract excerpt
The clinical impact of dendritic cells (DCs) in the treatment of human cancer depends on their unique role as the most potent antigen-presenting cells that are capable of priming an antitumor T-cell response. Here, we demonstrate that functional DCs can be generated from peripheral blood of patie...
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