Article
Dendritic cell phenotype can be improved by certain chemotherapies and is associated with alterations to p21(waf1/cip1.).
Cancer immunology, immunotherapy : CII - 1 Oct 2013
Liu Wai Man, Scott Katherine Ann, Thompson Mareike, Dalgleish Angus George
Abstract excerpt
INTRODUCTION: Dendritic cells (DCs) possess the capacity to elicit immune responses against harmful antigens and have been used in DC-vaccines to stimulate the immune system to engage cancer cells. However, a lack of an appreciation of the quality of the DC that is used and/or the monocyte from which it is derived has limited their successful incorporation into treatment strategies. METHODS: In the current study,...
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