Article
Characterization of murine dendritic cells derived from adherent blood mononuclear cells in vitro.
Scandinavian journal of immunology - 1 Aug 2000
Agger R, Petersen M S, Toldbod H E, Holtz S, Dagnaes-Hansen F, Johnsen B W, Bolund L, Hokland M
Abstract excerpt
The therapeutic potential of dendritic cells loaded with tumour antigens for the induction of effective immune responses against cancer is currently being tested in numerous clinical trials. In most cases, the dendritic cells are generated in vitro from peripheral blood monocytes. Many aspects of dendritic cell-based vaccination have not yet been examined in detail, and homologous mouse model systems may prove...
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