Article
Generation of a Bmp2 conditional null allele.
Genesis (New York, N.Y. : 2000) - 1 Jul 2005
Ma Lijiang, Martin James F
Abstract excerpt
Bone morphogenetic proteins (Bmp's) are known to play many important roles in embryogenesis. In addition, recent data from human genetic studies has revealed that Bmp's also have important functions in maintenance of the adult phenotype and aging. The original Bmp2 germline null allele resulted in lethality at embryonic day 7.0-10.5 due to malformation of the amnion/chorion and cardiac malformations. Because the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
