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Article

Generation of a floxed allele of the mouse BMP type II receptor gene.

Genesis (New York, N.Y. : 2000) - 1 Mar 2005

Beppu Hideyuki, Lei Hong, Bloch Kenneth D, Li En

Abstract excerpt

Bone morphogenetic proteins (BMPs) regulate a wide range of cellular functions that contribute to embryonic development from mesoderm formation to organogenesis. BMP type II receptor (BMPR-II) transduces BMP signals by forming heteromeric complexes with and phosphorylating BMP type I receptors. Heterozygous germline mutations of BMPR-II gene have been identified in patients with familial and sporadic primary...

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PMID: 15736264
DOI: 10.1002/gene.20099

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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