Article
The RET proto-oncogene: a challenge to our understanding of disease pathogenesis.
Pediatric surgery international - 1 Jan 1997
Kusafuka T, Puri P
Abstract excerpt
RET gene alterations as disease-causative mutations have been demonstrated in five different disease entities: Hirschsprung's disease (HD); papillary thyroid carcinoma; and three types of inherited cancer syndromes: multiple endocrine neoplasia (MEN) 2A, MEN 2B, and familial medullary thyroid car...
Topics
- Carcinoma, Papillary
- Drosophila Proteins
- Gene Expression
- Hirschsprung Disease
- Humans
- Multiple Endocrine Neoplasia Type 1
- Multiple Endocrine Neoplasia Type 2a
- Mutation
- Proto-Oncogene Mas
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-ret
- Proto-Oncogenes
- Receptor Protein-Tyrosine Kinases
- Thyroid Neoplasms
