Article
The CCR5-delta32 mutation: impact on disease outcome in individuals with hepatitis C infection from a single source.
Gut - 1 Aug 2005
Goulding C, McManus R, Murphy A, MacDonald G, Barrett S, Crowe J, Hegarty J, McKiernan S, Kelleher D
Abstract excerpt
BACKGROUND AND AIMS: Chemokines are small polypeptides, a major function of which is lymphocyte recruitment and trafficking. The aim of this study was to assess the involvement of inherited variations in CCR2, CCR5, and the ligand RANTES in determining disease outcome in hepatitis C virus (HCV) infected individuals. METHODS: A total of 283 women, all exposed to HCV genotype 1b from a single donor, and including...
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