Article
Chemokine receptor 5 polymorphism in myocardial infarction patients from Luxembourg.
Bulletin de la Societe des sciences medicales du Grand-Duche de Luxembourg - 1 Jan 2011
Rodius Sophie, Lambert Christine, Devaux Carole, Schmit Jean-Claude, Devaux Yvan, Wagner Daniel R
Abstract excerpt
BACKGROUND: The CC-chemokine receptor 5 (CCR5) is regulating inflammatory pathways and may thus be implicated in the development and progression of heart failure (HF). A 32 base pair deletion of the ccr5 gene, called CCR5delta32, prevents the expression of CCR5 at the cell surface. We analyzed the association between the CCR5delta32 deletion and the risk and severity of myocardial infarction (MI) in a cohort of...
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