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Article

Gefitinib-sensitive mutations of the epidermal growth factor receptor tyrosine kinase domain in chinese patients with non-small cell lung cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Jun 2005

Mu Xin Lin, Li Long Yun, Zhang Xiao Tong, Wang Men Zhao, Feng Rui E, Cui Quan Cai, Zhou Hai Sheng, Guo Bing Qing

Abstract excerpt

PURPOSE: Studies have shown that mutations in the epidermal growth factor receptor (EGFR) tyrosine kinase domain are associated with response of lung cancer to gefitinib (Iressa, AstraZeneca Corp., Shanghai, China). A higher incidence of EGFR mutation was observed in non-small cell lung cancer (NSCLC) patients of Japanese origin compared with those of American origin. However, no data about such mutations in...

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Identifiers

PMID: 15958609
DOI: 10.1158/1078-0432.CCR-04-2506

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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