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Article

Identification of EGFR kinase domain mutations among lung cancer patients in China: implication for targeted cancer therapy.

Cell research - 1 Mar 2005

Qin Bao Ming, Chen Xiao, Zhu Jing De, Pei Duan Qing

Abstract excerpt

Lung cancer is one of the leading causes of death with one of the lowest survival rates. However, a subset of lung cancer patients who are of Asian origin and carry somatic mutations in epidermal growth factor receptor or EGFR have responded remarkable well to two tyrosine kinase inhibitors, gefitinib and erlotinib. While EGFR mutation profiles have been reported from Japan, South Korea, and Taiwan, there is no...

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Source

Identifiers

PMID: 15780185
DOI: 10.1038/sj.cr.7290289

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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