Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

Identification of the Unique Clinical and Genetic Features of Chinese Lung Cancer Patients With EGFR Germline Mutations in a Large-Scale Retrospective Study

16 Nov 2021

Abstract excerpt

Background Epidemiological surveys have suggested that lung cancer has inherited susceptibility and shows familial aggregation. However, the distribution and prevalence of epidermal growth factor receptor ( EGFR ) germline variants and their roles in lung cancer genetic predisposition in Chinese population remain to be elucidated. Methods In this study, EGFR germline and somatic variants were retrospectively...

Source

Identifiers

PMID: 34869019
DOI: 10.3389/fonc.2021.774156

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Identification of the Unique Clinical and Genetic Features of Chinese Lung Cancer Patients With EGFR Germline Mutations in a Large-Scale Retrospective StudyPMID 34869019Read ↗

Clinical and genomic features of Chinese lung cancer patients with germline mutations.Semantic proximity Read ↗

Comprehensive genomic profiling of Chinese lung cancer characterizes germline-somatic mutation interactions influencing cancer riskSemantic proximity Read ↗

Characterization of common and rare mutations in EGFR and associated clinicopathological features in a large population of Chinese patients with lung cancer.Semantic proximity Read ↗

The co-mutation of EGFR and tumor-related genes leads to a worse prognosis and a higher level of tumor mutational burden in Chinese non-small cell lung cancer patientsSemantic proximity Read ↗

Clinical relevance of somatic mutations in Chinese lung adenocarcinoma and their prognostic implications for survival.Semantic proximity Read ↗

Spectrum of Pathogenic Germline Mutations in Chinese Lung Cancer Patients through Next-Generation Sequencing.Semantic proximity Read ↗

Profiling Oncogenic Germline Mutations in Unselected Chinese Lung Cancer PatientsSemantic proximity Read ↗

Catalog of Lung Cancer Gene Mutations Among Chinese PatientsSemantic proximity Read ↗

Precision oncology of lung cancer: genetic and genomic differences in Chinese populationSemantic proximity Read ↗

Comprehensive genomic profile of Chinese lung cancer patients and mutation characteristics of individuals resistant to icotinib/gefitinib.Semantic proximity Read ↗

Genetic profile of non-small cell lung cancer (NSCLC): A hospital-based survey in Jinhua.Semantic proximity Read ↗

Genomic Signature of Driver Genes Identified by Target Next-Generation Sequencing in Chinese Non-Small Cell Lung CancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.