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Article

Effect of the Toll-like receptor 4 (TLR-4) variants on intima-media thickness and monocyte-derived macrophage response to LPS.

Journal of internal medicine - 1 Jul 2005

Norata G D, Garlaschelli K, Ongari M, Raselli S, Grigore L, Benvenuto F, Maggi F M, Catapano A L

Abstract excerpt

OBJECTIVES: Toll-like receptor 4 (TLR-4) is believed to contribute to the initiation and progression of atherosclerosis. The association of the D299G polymorphism of the TLR-4 gene with the progression of coronary and carotid atherosclerosis, risk of cardiovascular events and myocardial infarction is controversial. We have investigated whether the presence of the D299G polymorphism and the co-segregated T399I...

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Source

Identifiers

PMID: 15953129
DOI: 10.1111/j.1365-2796.2005.01509.x

Genes

PTX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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