Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Toll-like receptor-4 Asp299Gly polymorphism does not influence progression of atherosclerosis in patients with familial hypercholesterolaemia.

European journal of clinical investigation - 1 Feb 2004

Netea M G, Hijmans A, van Wissen S, Smilde T J, Trip M D, Kullberg B J, de Boo T, Van der Meer J W M, Kastelein J J P, Stalenhoef A F H, Stalenhorf A F H

Abstract excerpt

BACKGROUND: Toll-like receptor-4 (TLR4) is a major receptor for inflammatory stimuli potentially involved in the pathogenesis of atherosclerosis, such as lipopolysaccharide (LPS) and heat-shock proteins. The Asp299Gly polymorphism of the TLR4 gene has been associated with a reduced intima-media t...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carotid Artery Diseases
Share to Hydroxymethylglutaryl-CoA Reductase Inhibitors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hyperlipoproteinemia Type II

Share to Inflammation Mediators

Share to Membrane Glycoproteins

Share to Receptors, Cell Surface

Share to Toll-Like Receptor 4

Share to Toll-Like Receptors

Source

Identifiers

PMID: 14764071
DOI: 10.1111/j.1365-2362.2004.01303.x

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-14764071-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Toll-like receptor-4 Asp299Gly polymorphism does not influence progression of atherosclerosis in patients with familial hypercholesterolaemia.PMID 14764071Read ↗

TLR4 Asp299Gly polymorphism is not associated with coronary artery stenosis.Semantic proximity Read ↗

Lack of association between TLR4 Asp299Gly polymorphism and atherosclerosis: evidence from meta-analysis.Semantic proximity Read ↗

Effect of the Toll-like receptor 4 (TLR-4) variants on intima-media thickness and monocyte-derived macrophage response to LPS.Semantic proximity Read ↗

The Asp299Gly Toll-like receptor 4 polymorphism in advanced aortic atherosclerosis.Semantic proximity Read ↗

Variants of toll-like receptor 4 modify the efficacy of statin therapy and the risk of cardiovascular events.Semantic proximity Read ↗

Association between Toll-like receptor 4 Asp299Gly polymorphism and coronary heart disease susceptibility.Semantic proximity Read ↗

Association of the Toll-like receptor 4 gene Asp299Gly polymorphism with acute coronary events.Semantic proximity Read ↗

Lack of the Toll-Like Receptor 4 Gene Polymorphisms Asp299Gly and Thr399ile in a Chinese Population.Semantic proximity Read ↗

Toll-like receptor 4 gene (Asp299Gly) polymorphism associates with carotid artery elasticity. The cardiovascular risk in young Finns study.Semantic proximity Read ↗

Toll receptor polymorphisms and carotid artery intima-media thickness.Semantic proximity Read ↗

Functional consequences of the Asp299Gly Toll-like receptor-4 polymorphism.Semantic proximity Read ↗

Toll-like receptor 4 gene Asp299Gly polymorphism is associated with reductions in vascular inflammation, angiographic coronary artery disease, and clinical diabetes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.