Article
Cell-specific regulation of oncogene-responsive sequences of the c-fos promoter.
Molecular and cellular biology - 1 Oct 1991
Gutman A, Wasylyk C, Wasylyk B
Abstract excerpt
We have identified oncogene-responsive sequences in the human c-fos promoter that mediate induction of transcription by several nonnuclear oncoproteins and the tumor promoter TPA. These sequences are regulated in a cell-specific manner. (i) In NIH 3T3 cells, the CArG box of the c-fos promoter is...
Topics
- Base Sequence
- Gene Expression Regulation, Neoplastic
- Genes, ras
- HeLa Cells
- Humans
- Molecular Sequence Data
- Mutation
- Promoter Regions, Genetic
- Proto-Oncogene Proteins c-fos
- Proto-Oncogenes
- Recombinant Fusion Proteins
- Regulatory Sequences, Nucleic Acid
- Tetradecanoylphorbol Acetate