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Article

Cell-specific regulation of oncogene-responsive sequences of the c-fos promoter.

Molecular and cellular biology - 1 Oct 1991

Gutman A, Wasylyk C, Wasylyk B

Abstract excerpt

We have identified oncogene-responsive sequences in the human c-fos promoter that mediate induction of transcription by several nonnuclear oncoproteins and the tumor promoter TPA. These sequences are regulated in a cell-specific manner. (i) In NIH 3T3 cells, the CArG box of the c-fos promoter is sufficient to mediate activation by oncogenes. (ii) In contrast, in HeLa cells, additional flanking sequences are also...

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Identifiers

PMID: 1922053
DOI: 10.1128/mcb.11.10.5381-5387.1991
PMCID: PMC361615

Genes

FAP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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