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Article

Cas mediates transcriptional activation of the serum response element by Src.

Molecular and cellular biology - 1 Oct 1999

Hakak Y, Martin G S

Abstract excerpt

The Src substrate p130(Cas) is a docking protein containing an SH3 domain, a substrate domain that contains multiple consensus SH2 binding sites, and a Src binding region. We have examined the possibility that Cas plays a role in the transcriptional activation of immediate early genes (IEGs) by v-Src. Transcriptional activation of IEGs by v-Src occurs through distinct transcriptional control elements such as the...

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Share to Adaptor Proteins, Vesicular Transport
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Oncogene Protein pp60(v-src)

Share to Protein Tyrosine Phosphatase, Non-Receptor Type 11

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Share to Retinoblastoma-Like Protein p130

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Source

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Identifiers

PMID: 10490632
DOI: 10.1128/MCB.19.10.6953
PMCID: PMC84690

Genes

EGF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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