Article
Variation in plasma insulin-like growth factor-1 and insulin-like growth factor binding protein-3: genetic factors.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Jun 2005
Morimoto Libby M, Newcomb Polly A, White Emily, Bigler Jeannette, Potter John D
Abstract excerpt
Insulin-like growth factors (IGFs) play key roles in cell proliferation and apoptosis. Whereas relatively stable within individuals, IGFs vary substantially between individuals, and a large component of this variation may be determined by genetic factors. Several polymorphisms in IGF genes have been identified, although their functional significance is not clear. We evaluated the association of polymorphisms in...
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