Article
Candidate polymorphisms and severe malaria in a Malian population.
PloS one - 1 Jan 2012
Toure Ousmane, Konate Salimata, Sissoko Sibiri, Niangaly Amadou, Barry Abdoulaye, Sall Abdourahmane H, Diarra Elisabeth, Poudiougou Belco, Sepulveda Nuno, Campino Susana, Rockett Kirk A, Clark Taane G, Thera Mahamadou A, Doumbo Ogobara
Abstract excerpt
Malaria is a major health burden in sub-Saharan African countries, including Mali. The disease is complex, with multiple genetic determinants influencing the observed variation in response to infection, progression, and severity. We assess the influence of sixty-four candidate loci, including the sickle cell polymorphism (HbS), on severe malaria in a case-control study consisting of over 900 individuals from...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
