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Article

Interleukin-1 gene cluster polymorphisms and susceptibility to clinical malaria in a Gambian case-control study.

European journal of human genetics : EJHG - 1 Feb 2004

Walley Andrew J, Aucan Christophe, Kwiatkowski Dominic, Hill Adrian V S

Abstract excerpt

Interleukin-1 (IL1) is a potent endogenous pyrogen and inducer of the acute phase response, and these innate immune responses are an important part of the human host's initial reaction to infection by the malaria parasite. In addition, several single-nucleotide polymorphisms (SNPs) in this region have previously been demonstrated to be associated with susceptibility to infectious disease. Therefore, a possible...

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PMID: 14673470
DOI: 10.1038/sj.ejhg.5201084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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