Article
Klp67A destabilises pre-anaphase microtubules but subsequently is required to stabilise the central spindle.
Journal of cell science - 15 Jun 2005
Gatt Melanie K, Savoian Matthew S, Riparbelli Maria G, Massarelli Chiara, Callaini Giuliano, Glover David M
Abstract excerpt
Klp67A is a member of the Kip3 subfamily of microtubule destabilising kinesins, the loss of which results in abnormally long and stable pre-anaphase microtubules. Here we examine its role during cytokinesis in Drosophila primary spermatocytes that require the coordinated interaction of an interior and peripheral set of central spindle microtubules. In mutants anaphase B spindles elongated with normal kinetics but...
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