Article
Mutations in orbit/mast reveal that the central spindle is comprised of two microtubule populations, those that initiate cleavage and those that propagate furrow ingression.
The Journal of cell biology - 5 Jul 2004
Inoue Yoshihiro H, Savoian Matthew S, Suzuki Takao, Máthé Endre, Yamamoto Masa-Toshi, Glover David M
Abstract excerpt
We address the relative roles of astral and central spindle microtubules (MTs) in cytokinesis of Drosophila melanogaster primary spermatocytes. Time-lapse imaging studies reveal that the central spindle is comprised of two MT populations, "interior" central spindle MTs found within the spindle envelope and "peripheral" astral MTs that probe the cytoplasm and initiate cleavage furrows where they contact the cortex...
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