Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Drosophila kinesin-like protein KLP3A is a midbody component required for central spindle assembly and initiation of cytokinesis.

The Journal of cell biology - 1 May 1995

Williams B C, Riedy M F, Williams E V, Gatti M, Goldberg M L

Abstract excerpt

We describe here a new member of the kinesin superfamily in Drosophila, KLP3A (Kinesin-Like-Protein-at-3A). The KLP3A protein localizes to the equator of the central spindle during late anaphase and telophase of male meiosis. Mutations in the KLP3A gene disrupt the interdigitation of microtubules in spermatocyte central spindles. Despite this defect, anaphase B spindle elongation is not obviously aberrant....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amino Acid Sequence
Share to Base Sequence

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cell Division

Share to Cloning, Molecular

Share to Drosophila

Share to Drosophila Proteins

Share to Genes, Insect

Share to Immunohistochemistry

Source

Open in PubMed Open full text

Identifiers

PMID: 7730406
DOI: 10.1083/jcb.129.3.709
PMCID: PMC2120429

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Drosophila kinesin-like protein KLP3A is a midbody component required for central spindle assembly and initiation of cytokinesis.PMID 7730406Read ↗

Klp67A destabilises pre-anaphase microtubules but subsequently is required to stabilise the central spindle.Semantic proximity Read ↗

The Drosophila kinesin-like protein KLP3A is required for proper behavior of male and female pronuclei at fertilization.Semantic proximity Read ↗

The chromokinesin, KLP3A, dives mitotic spindle pole separation during prometaphase and anaphase and facilitates chromatid motility.Semantic proximity Read ↗

Kinesin-related KIP3 of Saccharomyces cerevisiae is required for a distinct step in nuclear migration.Semantic proximity Read ↗

Mutations in orbit/mast reveal that the central spindle is comprised of two microtubule populations, those that initiate cleavage and those that propagate furrow ingression.Semantic proximity Read ↗

Kinesins klp5(+) and klp6(+) are required for normal chromosome movement in mitosis.Semantic proximity Read ↗

GOLPH3 is essential for contractile ring formation and Rab11 localization to the cleavage site during cytokinesis in Drosophila melanogaster.Semantic proximity Read ↗

A Drosophila kinesin-like protein, Klp38B, functions during meiosis, mitosis, and segmentation.Semantic proximity Read ↗

The chromokinesin Klp3a and microtubules facilitate acentric chromosome segregation.Semantic proximity Read ↗

The Drosophila kinesin-like protein KLP67A is essential for mitotic and male meiotic spindle assembly.Semantic proximity Read ↗

pkl1(+)and klp2(+): Two kinesins of the Kar3 subfamily in fission yeast perform different functions in both mitosis and meiosis.Semantic proximity Read ↗

A microtubule-destabilizing kinesin motor regulates spindle length and anchoring in oocytes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.