Article
A requirement for the Abnormal Spindle protein to organise microtubules of the central spindle for cytokinesis in Drosophila.
Journal of cell science - 1 Mar 2002
Riparbelli Maria Giovanna, Callaini Giuliano, Glover David M, Avides Maria do Carmo
Abstract excerpt
Drosophila abnormal spindle (asp) mutants exhibit a mitotic metaphase checkpoint arrest with abnormal spindle poles, which reflects a requirement for Asp for the integrity of microtubule organising centres (MTOCs). In male meiosis, the absence of a strong spindle integrity checkpoint enables asp mutant cells to proceed through anaphase and telophase. However, the central spindle region is not correctly organised...
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