Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Drosophila dd4 mutants reveal that gammaTuRC is required to maintain juxtaposed half spindles in spermatocytes.

Journal of cell science - 1 Mar 2003

Barbosa Vitor, Gatt Melanie, Rebollo Elena, Gonzalez Cayetano, Glover David M

Abstract excerpt

The weak spindle integrity checkpoint in Drosophila spermatocytes has revealed a novel function of the gamma-tubulin ring complex (gammaTuRC) in maintaining spindle bipolarity throughout meiosis. Bipolar and bi-astral spindles could form in Drosophila mutants for dd4, the gene encoding the 91 kDa subunit of gammaTuRC. However, these spindles collapsed around metaphase and began to elongate as if attempting...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Centrosome
Share to Microscopy, Confocal
Share to Microtubule-Associated Proteins

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Microtubule Proteins

Share to Microtubules

Share to Spermatocytes

Share to Spindle Apparatus

Share to Tubulin

Source

Identifiers

PMID: 12571290
DOI: 10.1242/jcs.00295

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Drosophila dd4 mutants reveal that gammaTuRC is required to maintain juxtaposed half spindles in spermatocytes.PMID 12571290Read ↗

Assembly and dynamics of an anastral:astral spindle: the meiosis II spindle of Drosophila oocytes.Semantic proximity Read ↗

Abnormal meiotic spindles cause a cascade of defects during spermatogenesis in asp males of Drosophila.Semantic proximity Read ↗

Regulation and execution of meiosis in Drosophila males.Semantic proximity Read ↗

Mutations in orbit/mast reveal that the central spindle is comprised of two microtubule populations, those that initiate cleavage and those that propagate furrow ingression.Semantic proximity Read ↗

Drosophila male meiosis as a model system for the study of cytokinesis in animal cells.Semantic proximity Read ↗

Spindle assembly and cytokinesis in the absence of chromosomes during Drosophila male meiosis.Semantic proximity Read ↗

The gammaTuRC components Grip75 and Grip128 have an essential microtubule-anchoring function in the Drosophila germline.Semantic proximity Read ↗

Mutation of a Drosophila gamma tubulin ring complex subunit encoded by discs degenerate-4 differentially disrupts centrosomal protein localization.Semantic proximity Read ↗

Klp67A destabilises pre-anaphase microtubules but subsequently is required to stabilise the central spindle.Semantic proximity Read ↗

A requirement for the Abnormal Spindle protein to organise microtubules of the central spindle for cytokinesis in Drosophila.Semantic proximity Read ↗

Male meiotic spindle features that efficiently segregate paired and lagging chromosomesSemantic proximity Read ↗

Anastral meiotic spindle morphogenesis: role of the non-claret disjunctional kinesin-like protein.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.