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Article

The Drosophila kinesin-like protein KLP67A is essential for mitotic and male meiotic spindle assembly.

Molecular biology of the cell - 1 Jan 2004

Gandhi Rita, Bonaccorsi Silvia, Wentworth Diana, Doxsey Stephen, Gatti Maurizio, Pereira Andrea

Abstract excerpt

We have performed a mutational analysis together with RNA interference to determine the role of the kinesin-like protein KLP67A in Drosophila cell division. During both mitosis and male meiosis, Klp67A mutations cause an increase in MT length and disrupt discrete aspects of spindle assembly, as well as cytokinesis. Mutant cells exhibit greatly enlarged metaphase spindle as a result of excessive MT polymerization....

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Identifiers

PMID: 13679514
DOI: 10.1091/mbc.e03-05-0342
PMCID: PMC307533

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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