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Article

Cooperative interactions between the central spindle and the contractile ring during Drosophila cytokinesis.

Genes & development - 1 Feb 1998

Giansanti M G, Bonaccorsi S, Williams B, Williams E V, Santolamazza C, Goldberg M L, Gatti M

Abstract excerpt

We analyzed male meiosis in mutants of the chickadee (chic) locus, a Drosophila melanogaster gene that encodes profilin, a low molecular weight actin-binding protein that modulates F-actin polymerization. These mutants are severely defective in meiotic cytokinesis. During ana-telophase of both meiotic divisions, they exhibit a central spindle less dense than wild type; certain chic allelic combinations cause...

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Identifiers

PMID: 9450933
DOI: 10.1101/gad.12.3.396
PMCID: PMC316479

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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