Article
A microtubule-destabilizing kinesin motor regulates spindle length and anchoring in oocytes.
The Journal of cell biology - 11 Feb 2008
Zou Jianwei, Hallen Mark A, Yankel Christine D, Endow Sharyn A
Abstract excerpt
The kinesin-13 motor, KLP10A, destabilizes microtubules at their minus ends in mitosis and binds to polymerizing plus ends in interphase, regulating spindle and microtubule dynamics. Little is known about kinesin-13 motors in meiosis. In this study, we report that KLP10A localizes to the unusual pole bodies of anastral Drosophila melanogaster oocyte meiosis I spindles as well as spindle fibers, centromeres, and...
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