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Article

Human serotonin 5-HT7 receptor: cloning and pharmacological characterisation of two receptor variants.

FEBS letters - 25 Aug 1997

Stam N J, Roesink C, Dijcks F, Garritsen A, van Herpen A, Olijve W

Abstract excerpt

Two splice variants of the 5-HT7 receptor were identified in human brain that differ in the lengths of their intracellular carboxy terminal tail. Identification of the variants of this receptor is of particular interest since the 5-HT7 receptor is known to have a high affinity for a number of antidepressants and is localized in brain regions thought to be implicated in depression. The two isoforms are expressed...

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Identifiers

PMID: 9303561
DOI: 10.1016/s0014-5793(97)00964-2

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