No association between E- and L-selectin genes and SLE: soluble L-selectin levels do correlate with genotype and a subset in SLE.

doi:10.1038/sj.gene.6364222

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Back to search

Article

No association between E- and L-selectin genes and SLE: soluble L-selectin levels do correlate with genotype and a subset in SLE.

Genes and immunity - 1 Aug 2005

Russell A I, Cunninghame Graham D S, Chadha S, Roberton C, Fernandez-Hart T, Griffiths B, D'Cruz D, Nitsch D, Whittaker J C, Vyse T J

Abstract excerpt

Altered function of selectin glycoprotein adhesion molecules may modulate severity and organ-specific manifestations of autoimmune and inflammatory disease via changes in leukocyte trafficking. Serum concentrations of selectin molecules have been suggested as useful biomarkers in systemic lupus e...

Topics

Adult
Antibodies, Antiphospholipid
Chromosomes, Human, Pair 1
E-Selectin
Female
Genetic Predisposition to Disease
Humans
L-Selectin
Lupus Erythematosus, Systemic
Male
Middle Aged
Polymorphism, Single Nucleotide
Quantitative Trait Loci
Risk Factors

Source

Open in PubMed

Identifiers

PMID: 15902275
DOI: 10.1038/sj.gene.6364222

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-15902275-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics