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Article

Variation in the upstream region of P-Selectin (SELP) is a risk factor for SLE.

Genes and immunity - 1 Jul 2009

Morris D L, Graham R R, Erwig L-P, Gaffney P M, Moser K L, Behrens T W, Vyse T J, Graham D S Cunninghame

Abstract excerpt

Systemic lupus erythematosus (SLE) is a complex autoimmune disease. Genome-wide linkage studies implicated a region containing the adhesion molecule P-Selectin. This family-based study revealed two regions of association within P-Selectin. The strongest signal, from a 21.4-kb risk haplotype, stretched from the promoter into the first two consensus repeat (CR) regions (P=8 x 10(-4)), with a second association from...

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Identifiers

PMID: 19404301
DOI: 10.1038/gene.2009.17
PMCID: PMC2834331

Genes

SELP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Variation in the upstream region of P-Selectin (SELP) is a risk factor for SLE.PMID 19404301Read ↗

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