Article
Clinical and genetic correlates of soluble P-selectin in the community.
Journal of thrombosis and haemostasis : JTH - 1 Jan 2008
Lee D S, Larson M G, Lunetta K L, Dupuis J, Rong J, Keaney J F, Lipinska I, Baldwin C T, Vasan R S, Benjamin E J
Abstract excerpt
BACKGROUND: P-selectin is a cell adhesion molecule that is involved in atherogenesis, and soluble concentrations of this biomarker reflect cardiovascular risk. However, the clinical correlates and genetic characterization of soluble P-selectin have not been clearly elucidated. OBJECTIVE: To descr...
Topics
- Aged
- Cardiovascular Diseases
- Female
- Genetic Linkage
- Humans
- Inheritance Patterns
- Male
- Middle Aged
- Multivariate Analysis
- P-Selectin
- Pedigree
- Phenotype
- Polymorphism, Single Nucleotide
- Residence Characteristics
- Risk Factors