Article
Association between single-nucleotide polymorphisms in selectin genes and immunoglobulin A nephropathy.
American journal of human genetics - 1 Mar 2002
Takei Takashi, Iida Aritoshi, Nitta Kosaku, Tanaka Toshihiro, Ohnishi Yozo, Yamada Ryo, Maeda Shiro, Tsunoda Tatsuhiko, Takeoka Sachiyo, Ito Kyoko, Honda Kazuho, Uchida Keiko, Tsuchiya Ken, Suzuki Yasushi, Fujioka Tomoaki, Ujiie Takashi, Nagane Yutaka, Miyano Satoru, Narita Ichiei, Gejyo Fumitake, Nihei Hiroshi, Nakamura Yusuke
Abstract excerpt
Although intensive efforts have been undertaken to elucidate the genetic background of immunoglobulin A nephropathy (IgAN), genetic factors associated with the pathogenesis of this disease are still not well understood. We designed a case-control association study that was based on linkage disequilibrium among single-nucleotide polymorphisms (SNPs) in the selectin gene cluster on chromosome 1q24-25, and we found...
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