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Bioinformatics Analyzes of Selectins Polymorphisms Reveal New Potential Cancer Biomarkers

2023-03-01

Abstract excerpt

Selectins are responsible for the early stages of cell migration as they control cell adhesion. They make the microenvironment permissive for metastatic events by promoting the activation of other cell adhesion molecules (CAMs). We employed several robust bioinformatics tools to evaluate gene sequence; single nucleotide polymorphisms (SNPs) in intronic and UTR regions; and missense SNPs with amino acid change in L...

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Literature Corpus work
fcf67b16-cf26-57cc-89fc-9908a576774f
DOI
10.20944/preprints202303.0014.v1
Open publication

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