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Article

Identification of novel susceptibility genes in childhood-onset systemic lupus erythematosus using a uniquely designed candidate gene pathway platform.

Arthritis and rheumatism - 1 Dec 2007

Jacob Chaim O, Reiff Andreas, Armstrong Don L, Myones Barry L, Silverman Earl, Klein-Gitelman Marisa, McCurdy Deborah, Wagner-Weiner Linda, Nocton James J, Solomon Aaron, Zidovetzki Raphael

Abstract excerpt

OBJECTIVE: Childhood-onset systemic lupus erythematosus (SLE) presents a unique subgroup of patients for genetic study. The present study was undertaken to identify susceptibility genes contributing to SLE, using a novel candidate gene pathway microarray platform to investigate gene expression in patients with childhood-onset SLE and both of their parents. METHODS: Utilizing bioinformatic tools, a platform of...

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Source

Identifiers

PMID: 18050247
DOI: 10.1002/art.23060

Genes

IRAK1
SELP

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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