Article
Sec15, a component of the exocyst, promotes notch signaling during the asymmetric division of Drosophila sensory organ precursors.
Developmental cell - 1 Sept 2005
Jafar-Nejad Hamed, Andrews Hillary K, Acar Melih, Bayat Vafa, Wirtz-Peitz Frederik, Mehta Sunil Q, Knoblich Juergen A, Bellen Hugo J
Abstract excerpt
Asymmetric division of sensory organ precursors (SOPs) in Drosophila generates different cell types of the mature sensory organ. In a genetic screen designed to identify novel players in this process, we have isolated a mutation in Drosophila sec15, which encodes a component of the exocyst, an evolutionarily conserved complex implicated in intracellular vesicle transport. sec15(-) sensory organs contain extra...
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