Article
Sec6 mutations and the Drosophila exocyst complex.
Journal of cell science - 15 Mar 2005
Murthy Mala, Ranjan Ravi, Denef Natalie, Higashi Misao E L, Schupbach Trudi, Schwarz Thomas L
Abstract excerpt
To allow a detailed analysis of exocyst function in multicellular organisms, we have generated sec6 mutants in Drosophila. We have used these mutations to compare the phenotypes of sec6 and sec5 in the ovary and nervous system, and we find them to be similar. We also find that Sec5 is mislocalized in sec6 mutants. Additionally, we have generated an epitope-tagged Sec8 that localized with Sec5 on oocyte membranes...
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