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Article

Association of a GNAS1 gene variant with hypertension and diabetes mellitus.

Hypertension research : official journal of the Japanese Society of Hypertension - 1 Dec 2004

Yamamoto Miyuki, Abe Michiko, Jin Jing Ji, Wu Zhihong, Tabara Yasuharu, Mogi Masaki, Kohara Katsuhiko, Miki Tetsuro, Nakura Jun

Abstract excerpt

Previous studies have shown that the T allele of the GNAS1 T393C polymorphism is associated with poor responsiveness to beta-blockade and that the T393C polymorphism interacts with cigarette smoking and alcohol consumption in the pathogenesis of hypertension. Thus, the T393C polymorphism is likely to interact with beta-adrenoceptor (beta-AR) stimulation in the pathogenesis of hypertension. Although this...

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Source

Identifiers

PMID: 15894831
DOI: 10.1291/hypres.27.919

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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