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Article

G protein polymorphisms in hypertension, atherosclerosis, and diabetes.

Annual review of medicine - 1 Jan 2005

Siffert Winfried

Abstract excerpt

A common C825T polymorphism in the gene GNB3, which encodes the beta 3 subunit of heterotrimeric G proteins, was identified in cell lines from patients with hypertension. The 825T allele is associated with increased intracellular signal transduction. Many population-based and case-control studies in different ethnicities have investigated an association between this polymorphism and hypertension, obesity, and...

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Source

Identifiers

PMID: 15660499
DOI: 10.1146/annurev.med.56.082103.104625

Genes

GNB3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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