Article
Association of the GNAS1 gene variant with hypertension is dependent on alcohol consumption.
Hypertension research : official journal of the Japanese Society of Hypertension - 1 Jun 2003
Chen Yusen, Nakura Jun, Jin Jing-Ji, Wu Zhihong, Yamamoto Miyuki, Abe Michiko, Tabara Yasuharu, Yamamoto Yoshikuni, Igase Michiya, Bo Xiao, Kohara Katsuhiko, Miki Tetsuro
Abstract excerpt
The beta-adrenoceptor (beta-AR)-stimulatory guanine nucleotide-binding (Gs) protein system has been shown to play important roles in the cardiovascular system. The gene encoding the alpha-subunit of Gs proteins (GNAS1) is a candidate genetic determinant for hypertension. Because alcohol consumpti...
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