Article
G-Protein β3-Subunit Gene C825T Polymorphism and Cardiovascular Risk: An Updated Review.
High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension - 1 Sept 2015
Semplicini Andrea, Grandi Tommaso, Sandonà Chiara, Cattelan Arianna, Ceolotto Giulio
Abstract excerpt
Hypertension is a common disorder of multifactorial origin that constitutes a major risk factor for cardiovascular events such as stroke and myocardial infarction. The subunits of the heterotrimeric G proteins are attractive candidate gene products for susceptibility to hypertension, obesity and insulin resistance syndrome. A polymorphism (825C/T) in exon 10 of the GNB3 gene, encoding for the Gβ3 subunit, has...
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